浙江大学化学系研究生导师介绍：祝莹

姓名：祝莹
单位：化学系
职称：特聘副研究员，硕士生导师
基本信息
个人简介
Research ID
http://www.researcherid.com/rid/B-6637-2011
2013.1-至今 浙江大学，化学系，特聘副研究员，硕士生导师
2010.6-2013.1 浙江大学，控制系，智能系统与控制研究所，博士后（导师，方群教授，牟颖教授）
2012.1-2012.4 National University of Singapore（新加坡国立大学），化学系，访问学者（合作导师，Prof. Shaoqin Yao）
2005.9-2010.6 浙江大学，化学系，微分析系统研究所，博士（导师，方群教授）
2001.9-2005.6 浙江大学，化学系，学士
工作研究领域
（1）超微量、高通量的微流控筛选仪器，并用于药物筛选和蛋白质结晶筛选；
（2）新型微型化电喷雾质谱离子源的研制以及用于药物筛选和单细胞分析；
（3）基于激光诱导荧光的单分子和单细胞分析方法；
（4）基于微流控芯片的微型化色谱分离和检测装置。
联系方式
电话：+86+57188206771
电子信箱：yingzhu#zju.edu.cn
研究成果
1. 超微量、高通量微流控液体操纵和检测装置
研制了一种基于液滴微流控技术的全自动液体操纵和检测装置。该装置可高度可靠的进行皮升级液体定量量取、混合、转移、检测、以及生化筛选。与常规基于384孔板的筛选系统相比，其试样消耗降低了37000倍以上。目前，该装置获得了2011年度浙江大学自研自制仪器设备优秀成果奖。
实验室介绍
浙江大学紫金港校区化学楼101 房间（Lab）
浙江大学紫金港校区化学楼104房间（Office）
发表论文
2013
[1] Yingzhu,Yunxia Zhang,Longfei Cai,Qun Fang,Sequential Operation Droplet Array: An Automated Microfluidic Platform for Picoliter-Scale Liquid Handling,Analysis,and Screening,Analytical Chemistry,2013,85(14): 6723–6731 fck_filebrowser.php
[2] Ying Zhu,* Nian-Nian Chen,* Qi Li,Qun Fang,Improving the sensitivity of confocal laser induced fluorescence detection to sub-picomolar scale for round capillaries by laterally shifting laser focus point,Analyst,2013,138,4642-4648fck_filebrowser.php (*coauthors)
[3] Ying Zhu,Qun Fang,Analytical detection techniques for droplet microfluidics—A review,Analytica Chimica Acta,2013,787,24-35 fck_filebrowser.php
[4] Yuan Su,Ying Zhu,Qun Fang,A multifunctional microfluidic droplet-array chip for analysis by electrospray ionization mass spectrometry,Lab on a Chip,2013,13(10),1876-1882
[5] Qi Li,Ting Zhang,Ying Zhu,Qun Fang,Automated high-speed CE system for multiple samples,Electrophoresis,2013,34(4),557-561
2012
[1]Ying Zhu,Hong Chen,Guansheng Du,Qun Fang. Microfluidic Droplet-Array Liquid-Liquid Chromatography based on Droplet Trapping Technique. Lab on a Chip,2012,12(21): 4350–4354fck_filebrowser.php
[2]Long-fei Cai,* Ying Zhu,* Qun Fang,Droplet-based Microfluidic Flow Injection System with Large-Scale Concentration Gradient by a Single Nanoliter-Scale Injection for Enzyme Inhibition Assay,Analytical Chemistry,2012,84(1): 446-452 (*同等贡献)fck_filebrowser.php
[3] Xiuli Wang,Ying Zhu,Qun Fang,Valveless gated injection for microfluidic chip-based liquid chromatography system with polymer monolithic column,Journal of Chromatography A,2013,1246,123-128
[4]Ji-feng Fan,Ying Zhu,Xiao-tong Shi,Qun Fang,Jiang Huang,Microfluidic sequential injection analysis system based on polydimethylsiloxane (PDMS) chip with integrated pneumatic-actuated valves,Science china-chemistry,2012,55(4): 531-536
2011
[1]Yun-xia Zhang,* Ying Zhu,* Bo Yao,Qun Fang. Droplet Array for Real Time Reverse Transcription Polymerase Chain Reaction,Lab on a Chip,2011,11(8):1545-1559 (*同等贡献)
[2]Ze-Qi Yu,Ying Zhu,Yunxia Zhang,Juan Li,Qun Fanga,Jianzhong Xi,Bo Yao,Nanoliter droplet array for microRNA detection based on enzymatic stem-loop probes ligation and SYBR Green real-time PCR,Talanta,2011,85 (4): 1760-1765
[3]Shu-Qing Gu,Yun-Xia Zhang,Ying Zhu,Wen-Bin Du,Bo Yao,Qun Fang,Multifunctional picoliter droplet manipulation platform and its application in single cell analysis. Analytical Chemistry,2011,83(19):7570-7576
[4]Xin-Jue Wang,Ying Zhu,Qun Fang,Developments and applications of microfluidic chip-based chromatographic technique,Chinese Journal of Chromatography,2011,29(2): 99-104
2010
[1]Ying Zhu,Qun Fang. Integrated Droplet Analysis System with Electrospray Ionization-Mass Spectrometry Using a Hydrophilic Tongue-based Droplet Extraction Interface. Analytical Chemistry,2010,82(19): 8361-8366fck_filebrowser.php
[2]Ying Zhu,Jian-zhang Pan,Yuan Su,Qiao-hong He,Qun Fang. Fabrication of Low-Melting-Point Alloy Microelectrode and Monolithic Spray Tip for Integration of Glass Chip with Electrospray Ionization Mass Spectrometry. Talanta,2010,81(3):1069-1075fck_filebrowser.php
[3]Wen-bin Du,* Meng Sun,* Shu-qing Gu,* Ying Zhu,* Fang Qun. Automated Microfluidic Screening Assay Platform based on DropLab. Analytical Chemistry,2010,82(23): 9941-9947 (*同等贡献）
[4]Qing-Hu Lin,Yong-Qiang Cheng,Ya-Ni Dong,Ying Zhu,Jian-Zhang Pan,Qun Fang,High-speed separation of proteins by sodium dodecyl sulfate-capillary gel electrophoresis with partial translational spontaneous sample injection,Electrophoresis,2011,32(20): 2898-2903
会议论文
[1]Qun Fang,Ying Zhu,Hong Chen. Microfluidic chip-based droplet-array liquid-liquid chromatography. Proceedings of the First Shenyang International Colloquium on Microfluidics. Shenyang,China,2007,256~258（报展）
[2]Ying Zhu,Jian-Zhang Pan,Yuan Su,Qun Fang. A microfluidic chip based electrospray interface for mass spectrometry with a low-temperature alloy microelectrode. Twelfth International Conference on Miniaturized Systems for Chemistry and Life Sciences. San Diego,USA,2008,976~978（报展）
[3]Ying Zhu,Hong Chen,Qun Fang. Droplet-array liquid chromatography on a microfluidic chip using droplet trapping technique. The 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Kyoto,Japan,2008,147 （口头报告）
[4]Ying Zhu,Jian-Zhang Pan,Yuan Su,Qun Fang. A novel interface for electrospray ionization mass spectrometry on a microfluidic glass chip. The 5th National Conference on Micro-Total Analytical Systems,Nanjing,China,2008,188（报展）
[5]Ying Zhu,Hong Chen,Qun Fang. Droplet-array liquid chromatography on a microchip. Thirteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Jeju,Korea,2009,1470~1472（报展）
[6]Ying Zhu,Qun Fang. Droplet analysis with electrospray ionization mass spectrometry using an integrated glass microchip,Fourteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Groningen,The Netherlands,2010,1352~1354 (口头报告)
[7]Ying Zhu,Qun Fang,Integrated microfluidic chip for droplet analysis based on electrospray ionization mass spectrometry,The 6th National Conference on Micro-Total Analytical Systems,Shanghai,China,2010（报展）
[8]Yuan Su,Ying Zhu,Qun Fang,A multifunctional microfluidic droplet array system with ESI-MS detection,Fifteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences. Seattle,USA,2011,586~589（报展）
[9]Yun-Xia Zhang,Ying Zhu,Bo Yao,Qun Fang. Nanoliter droplet array for digital PCR. The 37rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Dalian,2011,316（报展）
[10]Xiu-Li Wang,Ying Zhu,Qun Fang. Microchip-based valveless high performance liquid chromatography system with gated injection. The 37rd International Symposium on High Performance Liquid Phase Separations and Related Techniques. Dalian,2011,315（报展）
[11]Ying Zhu,Yunxia Zhang,Longfei Cai,Qun Fang,High throughput and picoliter-scale drug screening with automated droplet microarray system,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,389-391（报展）
[12]Yun-Xia Zhang,Ying Zhu,Qun Fang,Bo Yao,Single cell microRNA quantification with two step RT-Q-PCR based on flexible nanoliter-scale droplet array system,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,428-430（报展）
[13]Xiu-Li Wang,Ying Zhu,Qun Fang,Droplet analysis system using liquid chromatography and mass spectrometry for enzyme inhibition assay,The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Okinawa,Japan,2012,1921-1923（报展）
[14]Li-na Zhu,Ying Zhu,Qun Fang Nanoliter-Scale Screening of Protein Crystallization with Sequential Operation Droplet Array,The 5th International Symposium on Microchemistry and Microsystems,Xiamen,China,2013 （报展,CHEMINAS POSTER AWARD）
[15]Ying Zhu,Nian-nian Chen,Qi Li,and Qun Fang,Laterally Shifting Laser Focus Point on Round Capillary can Improve the Sensitivity of Confocal Laser Induced Fluorescence Detection to Sub-picomolar Scale,The 5th International Symposium on Microchemistry and Microsystems,Xiamen,China,2013 （口头报告）
研究生招生
每年招收硕士生2~3名，博士生1~2名，欢迎对分析仪器研制、微流控分析新方法、质谱分析学研究有兴趣的同学报考
正在进行的研究项目
1．多通道微量液滴点样仪的研制
2．高通量电喷雾质谱分析系统的研究
3．蛋白质结晶新方法研究
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